Current medical management of Coronary Artery Disease (CAD) involves a two-pronged approach – to relieve symptoms and reduce the risk of cardiovascular events.

This is combined with lifestyle modification, which is an important step in both preventing CAD and improving the prognosis in patients with stable CAD.

  • Symptomatic treatment of CAD is intended to reduce angina symptoms and improve exercise capacity and quality of life.
  • Cardioprotective therapy for CAD is aimed at reducing the risk of myocardial infarction and heart failure, and prolonging life.6

Medical procedures are also used in the treatment of CAD; however the COURAGE results reinforce clinical practice guidelines stating that optimal medical treatment should be the initial management approach in patients with stable CAD, even if extensive and multivessel atherosclerosis is involved.

Despite lifestyle modifications, current treatment options and surgical techniques, cardiovascular disease remains a problem, and there exists a clear need for new and effective preventative treatments.

Newer treatment options include selective If inhibitors which relieve angina symptoms, boost exercise capacity by selectively reducing resting heart rate, and could improve cardiovascular prognosis in coronary patients13 with elevated heart rate ( HR > 70 bpm)

References:

6. The CLARIFY Registry: Management of Stable Coronary Artery Disease in Clinical Practice. Brochure for participating doctors. Edited by G Steg on behalf of the BEAUTIFUL Executive Committee.
13. Fox K, Ford I, Steg PG et al. Ivabradine for patients with stable coronary artery disease and left ventricular dysfunction (Beautiful): a randomized, double-blind, placebocontrolled trial. Lancet. 2008; 372: 807–816.